Abstract:Objective To analyze the influencing factors for lower extremity deep vein thrombosis (DVT), a common complication after total hip arthroplasty (THA), in elderly patients. Methods A retrospective analysis was conducted on 378 patients who underwent THA in Northern Jiangsu People’s Hospital from September 2022 to September 2023. The patients were divided into a DVT group (n=34) and a non-DVT group (n=344) according to whether DVT was happend or not . Univariate analysis was performed to compare preoperative, intraoperative and postoperative clinical data between the two groups. Multivariate logistic regression analysis was employed to identify independent influencing factors for DVT following THA and to construct a predictive model. Results Univariate analysis showed there were significant differences between the two groups (P<0.05) in the following factors: age ≥65 years (χ²=8.765), diabetes (χ²=7.462), intraoperative blood loss (χ²=5.451), blood transfusion (χ²=69.232), preoperative activated partial thromboplastin time (APTT) (Z=3.317), preoperative albumin (Z=3.974), preoperative hemoglobin (Z=3.341), postoperative hemoglobin (t=2.030), and postoperative albumin (Z=4.268). Multivariate logistic regression analysis indicated that age, diabetes, intraoperative blood loss, blood transfusion, preoperative APTT, and postoperative albumin were independent influencing factors for lower extremity DVT after THA (P<0.05). A nomogram risk prediction model was developed, and the calibration curve demonstrated good fit. The predictive performance of the nomogram was evaluated using the concordance index, which indicated that the model had favorable predictive ability. Conclusion Age, diabetes, intraoperative blood loss, intraoperative blood transfusion, preoperative APTT, and postoperative albumin are independent influencing factors for DVT following THA. The constructed nomogram model exhibits good predictive value.