Abstract:Coronary artery atherosclerotic heart disease（coronary heart disease），as acommon and frequently-occurring disease，the early diagnosis and treatment are of great significance to clinical prognosis. Traditional echocardiography has poor image quality due to poor acoustic window and other factors in patients，while myocardial contrast echocardiography（MCE）can improve the effect of endocardial boundary myocardial development by injecting ultrasound enhancers，and can also evaluate myocardial microcirculation perfusion，viable myocardium and coronary artery stenosis degree，thus improving the accuracy of diagnosing coronary heart disease. The development of MCE in preoperative and postoperative evaluation of interventional therapy and thrombolysis under high mechanical index provides anew imaging idea for scientific and accurate treatment of coronary heart disease.