Abstract:Objective To investigate the changes of hemodynamic indicators over time after neuromuscular electrical stimulation（NMES）in the prevention of the formation of deep venous thrombosis（DVT）in critically ill patients. Methods Forty patients in the intensive care unit（ICU）from the First Affiliated Hospital of Shandong First Medical University from June 2024 to August 2024 were selected as the research objects. Hemodynamic indicators of the popliteal vein［peak blood flow velocity（PFV），blood flow，vessel diameter］were collected by Doppler ultrasound before NMES application，30 min，1 h，1.5 h，2 h after NMES application，and 30 min，1 h after NMES discontinuation. Their temporal change patterns were analyzed. Results There were significant statistical differences in PFV，vessel diameter，and blood flow of popliteal vein across all time points in the 40 patients at different time points when NMSE was applied（χ2 =179.767，F=92.058，F=196.013，P<0.01）. Comparison at different time points showed that PFV，vessel diameter，and blood flow at 30 min，1 h，1.5 h，and 2 h after NMES application were all higher than those before NMES application（P<0.05），and the three indicators returned to the baseline levels before NMES application 1 h after discontinuation. However，PFV fluctuated and decreased at 1.5 h after NMES application，and then rose again and stabilized at the peak level at 1 h after 2 h of application. Conclusion NMES can accelerate the venous blood flow in the lower limbs of critically ill patients，and the peak stable period is reached after 1 h of NMES application. It is recommended that the single use duration of NMES for DVT prevention in critically ill patients should not be less than 1 h，the application frequency should be increased，and the interval between two sessions should not exceed 1 h.