Abstract:The glycemic risk index（GRI）is a comprehensive novel metric based on continuous glucose monitoring （CGM）. By differentiated weighting different glucose ranges，it integrates the exposure levels and duration of both hypoglycemia and hyperglycemia，allowing for more precise quantification of glucose exposure. Recent studies have shown that GRI is independently associated with the risk assessment of diabetic microangiopathy and macroangiopathy complications. GRI also demonstrates high sensitivity in improving extreme glucose events in automated insulin delivery system intervention studies，showing advantages over traditional glucose monitoring metrics in certain aspects. GRI is a new tool for predicting risks of diabetic complications，evaluating intervention effects，and enabling is management. However， further validation of clinical thresholds and general applicability of GRI is still needed.