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投稿时间:2024-05-24 网络发布日期:2025-11-26
投稿时间:2024-05-24 网络发布日期:2025-11-26
中文摘要: 嗜酸性粒细胞性食管炎是一种以食管嗜酸性粒细胞增多和食管功能障碍为特征的慢性炎性疾病。该疾病的治疗目标在于改善炎症和预防食管重塑,其治疗方式包括饮食疗法(基本饮食和消除饮食)、药物治疗[质子泵抑制剂和糖皮质激素(如布地奈德)]、生物制剂(度普利尤单抗、美泊利珠单抗、瑞利珠单抗、贝那利珠单抗、利伦替利单抗)以及内镜干预。随着对发病机制研究的深入,目前对于嗜酸性粒细胞性食管炎的治疗又有了新的进展,现对嗜酸性粒细胞性食管炎的现有及最新治疗方案进行综述,旨在为临床决策提供帮助。
Abstract:Eosinophilic esophagitis is a chronic inflammatory disease characterized by esophageal eosinophilia and esophageal dysfunction. The therapeutic goals of the disease are to improve inflammation and prevent esophageal remodeling. Its treatment methods
include dietary therapy(basic diet and elimination diet),drug treatment[proton pump inhibitors and glucocorticoids(e.g.,budesonide)],biological agents(dupilumab,mepolizumab,reslizumab,benralizumab,and lebrikizumab),and endoscopic intervention. With the deepening of research on the pathogenesis,there have been new advances in the treatment of eosinophilic esophagitis. This article reviews the existing and latest treatment options for eosinophilic esophagitis,aiming to provide assistance for clinical decision-making.
keywords: Eosinophilic esophagitis Eosinophils Targeted elimination diet Proton pump inhibitors Glucocorticoids Dupilumab Mepolizumab Reslizumab Benralizumab
文章编号: 中图分类号:R571 文献标志码:A
基金项目:山西省基础研究计划项目(202203021221259)
附件
| Author Name | Affiliation |
| LIU Yinjie*,MA Ruijun | *The Fifth Clinical Medical College,Shanxi Medical University,Taiyuan,Shanxi 030001,China |
引用文本:
刘银洁,马瑞军.嗜酸性粒细胞性食管炎治疗的研究进展[J].中国临床研究,2025,38(11):1781-1784.
刘银洁,马瑞军.嗜酸性粒细胞性食管炎治疗的研究进展[J].中国临床研究,2025,38(11):1781-1784.
