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中国临床研究英文版:2024,37(1):152-155,160
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重症肺炎患儿标准化急救中吸氧方案的优化及其急救效果
(南京医科大学附属儿童医院急诊抢救观察室,江苏 南京 210008)
Effect of optimization of oxygen inhalation scheme in standardized emergency treatment of children with severe pneumonia
(Department of Emergency Medicine, Childrens Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, China)
摘要
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Received:April 06, 2023   Published Online:January 09, 2024
中文摘要: 目的 探讨重症肺炎患儿标准化急救中吸氧方案的优化及其急救效果和临床症状的改善情况。 方法 选择2020年6月至2022年6月在南京医科大学附属儿童医院接受诊治的148例重症肺炎患儿,按照随机数字表法分为研究组和对照组,各74例。对照组采用一般急救护理,研究组采用标准化急救护理结合优化的吸氧方案(吸痰前预吸100%氧气5 min)。比较两种护理方式的效果、抢救时间、住院时间、并发症发生率、临床症状改善时间及血清C反应蛋白(CRP)、白细胞介素(IL)-6、IL-8、肿瘤坏死因子α (TNF-α)、血氧饱和度水平。 结果 研究组抢救时间、住院时间短于对照组,止咳时间、退热时间、气促消失时间早于对照组(P<0.01)。研究组并发症发生率(5.41% vs 16.22%, χ2=4.485,P<0.05)低于对照组。护理干预后两组患儿血清CRP、IL-6、IL-8、TNF-α 水平较干预前明显降低,其中研究组低于对照组(P<0.05)。研究组吸痰时、吸痰后5 min的血氧饱和度均高于对照组和吸痰前5 min,差异有统计学意义(P<0.01)。 结论 标准化急救护理结合优化的吸氧方案可加快重症肺炎患儿临床症状的恢复,有效维持血氧饱和度水平,降低炎症反应,提高急救效果。
Abstract:Objective To explore the optimization of oxygen inhalation scheme in standardized emergency treatment for children with severe pneumonia and the improvement of emergency effect and clinical symptoms of children. Methods A total of 148 children with severe pneumonia admitted to the Childrens Hospital of Nanjing Medical University from June 2020 to June 2022 were selected and randomly divided into the study group and the control group, with 74 cases in each group. The control group was treated with general emergency care, while the study group was treated with standardized emergency care combined with an optimized oxygen inhalation scheme (preoxygenation with 100% oxygen for 5 min before sputum suction). The nursing effects, time of resuscitation, hospital stay, complication rate, improvement time of clinical symptoms, and serum C-reactive protein (CRP), interleukin (IL)-6, IL-8, tumor necrosis factor-α (TNF-α) and blood oxygen saturation levels were compared between two groups. Results The rescue time, hospital stay of the study group were shorter, and cough relieving time, fever relieving time and dyspnea disappearance time were earlier than those of the control group (P<0.01). The complication rate (5.41% vs 16.22%, χ2=4.485, P<0.05) in the study group was lower than that in the control group. The serum levels of CRP, IL-6, IL-8 and TNF-α of the two groups of children after nursing intervention were decreased and the above indicators levels in the study group were significantly lower than those in the control group (P<0.05). The blood oxygen saturation of the study group at the time of sputum suction and 5 minutes after sputum suction was higher than that of the control group, with statistically significant differences (P<0.01). Conclusion Standardized emergency care combined with an optimized oxygen inhalation scheme can accelerate the recovery of clinical symptoms in children with severe pneumonia, maintain the level of blood oxygen saturation effectively, reduce inflammatory reactions, and improve the effect of emergency treatment.
文章编号:     中图分类号:R473.5    文献标志码:B
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