Abstract:Objective To investigate the effect of refined nursing in operation room on postoperative infection of open tibiofibular fractures with skin defects. Methods From January 2018 to December 2020, a total of 86 patients with open tibiofibular fractures combined with skin defects who received treatment at Department of Orthopedics, Huai'an First People's Hospital were analyzed retrospectively. The patients were divided into observation group (n=44) and control group (n=42) randomly. The control group received routine nursing measures, while the observation group received refined nursing interventions in the operating room. The incidence of postoperative infections, healing time of surgical incisions and fractures, postoperative hospital stay time, and nursing satisfaction between the two groups of patients were recorded and compared. Results The observation group showed better wound healing than the control group (Z=2.833, P=0.005). Compared with the control group, the observation group had shorter postoperative incision healing time ［(14±5) d vs (18±8) d, t=2.794, P=0.006］, fracture healing time ［(60±13) d vs (68±11) d, t=3.074, P= 0.003］, and postoperative hospitalization time ［(21±7) d vs (32±7) d, t=7.0274, P<0.001］. The nursing satisfaction of patients in the observation group was significantly higher than that of the control group (97.73% vs 78.57%, χ²=5.922, P=0.015). No pressure ulcers occurred in both groups of patients after surgery. Conclusion Implementing refined nursing interventions in the operating room for patients with open tibiofibular fractures and skin defects can significantly reduce postoperative infection complications, promote postoperative recovery, and improve patient nursing satisfaction.