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中国临床研究英文版:2023,36(6):958-960,封三
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加速康复外科方案下的胃肠癌术前术后体成分的测定与分析
(南京中医药大学附属医院普外科, 江苏 南京 210029)
Measurement and analysis of body composition in patients with gastrointestinal cancer before and after surgery under enhanced recovery after surgery
(Department of General Surgery, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210029, China)
摘要
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Received:September 21, 2022   Published Online:June 20, 2023
中文摘要: 目的 采用生物电阻抗测定法对加速康复外科(ERAS)方案下的胃肠癌手术患者进行体成分分析,比较胃癌和肠癌患者术后与术前体成分的变化趋势。 方法 选择2018年7月至2019年12月在江苏省中医院行胃肠癌手术患者共246例,其中胃癌组100例及肠癌组146例,在术前和术后6、12个月进行体成分监测,并进行统计分析。 结果 胃癌组患者术后6、12个月较术前,体成分各项指标均有不同程度的下降,差异有统计学意义(P<0.01);肠癌组患者的体重、BMI、体脂肪较术前增加(P<0.01),而蛋白质、肌肉量、瘦组织群、骨骼肌术后较术前差异无统计学意义(P>0.05)。术后6个月有15.53%的胃癌患者恢复至术前体重,有56.67%的肠癌患者恢复至术前体重;术后12个月,胃癌组患者恢复至术前体重比例未增加,肠癌患者恢复至术前体重增至65.33%。 结论 在ERAS方案下,胃癌和肠癌患者均短期快速康复出院,但其术后远期的体成分呈现不同的变化规律。胃癌患者术后营养情况较术前显著恶化,而肠癌患者术后营养状况有改善趋势。胃癌患者术后营养风险更高,需要重视并探索胃癌患者的营养治疗新策略。
中文关键词: 胃癌  肠癌  加速康复外科  营养不良  体成分
Abstract:Objective To analyze the body compositions of patients with gastrointestinal cancer after surgery under the enhanced recovery after surgery (ERAS) by bioelectrical impedance spectroscopy (BIS) to compare the change trend of postoperative and preoperative body composition in gastric cancer patients and intestinal cancer patients. Methods A total of 246 patients with gastrointestinal cancer receiving surgery at Jiangsu Province Hospital of Chinese Medicine from July 2018 to December 2019 were selected, including 100 cases in gastric cancer group and 146 cases in intestinal cancer group. Body composition monitoring and statistical analysis were performed before and 6 and 12 months after surgery in two groups. Results In gastric cancer group, compared with preoperative, all body composition indicators of patients decreased statistically at 6 and 12 months after surgery (P<0.01) . After surgery in intestinal cancer group, body weight, BMI and body fat increased compared with those before surgery (P<0.01) , but there were no statistical differences in protein level, muscle mass, lean tissue mass and skeletal muscle mass (P>0.05) . At 6 months after surgery, only 15.53% of gastric cancer patients returned to their preoperative weight, while 56.67% of colorectal cancer patients returned to their preoperative weight. At 12 months after surgery, there was no increase of proportion of patients returned to preoperative body weight in gastric cancer group, while 65.33% of patients recovered to their preoperative weight in intestinal cancer group. Conclusion Under the ERAS protocol, all gastrointestinal cancer patients recovered quickly and discharged from hospital, but the body composition showed different changes in the long term after surgery. The nutritional status of patients with gastric cancer significantly deteriorate compared with that before surgery, while the nutritional status of patients with intestinal cancer show a trend of improvement. The patients with gastric cancer have a higher nutritional risk after surgery and should be paied with more attention and new strategies for nutritional treatment.
文章编号:     中图分类号:R735    文献标志码:B
基金项目:江苏省中医药管理局重点项目 (ZD201903); 江苏省中医药局科技项目 (JD201807)
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