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Received:May 12, 2021 Published Online:November 20, 2021
Received:May 12, 2021 Published Online:November 20, 2021
中文摘要: 目的 探讨10年间空回肠疾病患者的疾病谱变迁情况。方法 回顾性收集2011年1月至2020年12月在中国人民解放军联勤保障部队第九四○医院消化内科行小肠镜检查且住院患者的临床资料，依据5年为一时间节点，患者分为A组（2011—2015年，n=61）和B组（2016—2020年，n=176）。分析10年间空回肠疾病的疾病谱变迁情况。结果 （1）空回肠疾病中，回肠疾病最多，为138例（58.38%），空肠疾病99例（41.77%）；以男性较多，男179例（75.53%），女58例（24.47%），男女比为4.09∶1。（2）空回肠疾病疾病谱前3位依次为溃疡62例（26.16%），非特异性炎症50例（21.10%），憩室35例（14.77%）；空肠的前5位疾病谱依次为空肠炎22例（22.22%<），恶性肿瘤15例（15.15%），空肠溃疡14例（14.14%），空肠毛细血管扩张症9例（9.09%），空肠间质瘤7例（7.07%）；回肠的前5位疾病谱依次为回肠溃疡48例（34.78%），回肠憩室29例（21.01%），回肠炎28例（20.29%），回肠毛细血管扩张症10例（7.25%），回肠毛细血管畸形5例（3.62%）；（3）与A组相比，B组男性比例高(χ2=14.640,P<0.01)，B组空回肠疾病患者的增长趋势更加明显。结论 10年间空回肠疾病总趋势仍呈现增长趋势，且不同性别的患病情况需要引起临床关注。
Abstract:Objective To explore the changes of disease spectrum in patients with jejunal and ileal diseases in the past 10 years. Methods The clinical data of inpatients undergoing enteroscopy from January 2011 to December 2020 were collected and analyzed retrospectively. Based on a time period of five years, the patients were divided into group A (2011 to 2015, n=61) and group B (2016 to 2020, n=176). The changes of disease spectrum in jejunal and ileal diseases were analyzed. Results There were 138 cases of ileal diseases (58.38%) and 99 cases of jejunal diseases (41.77%), with 179 males (75.53%) and 58 females (24.47%). The top three diseases in the disease spectrum of jejunum and ileum were ulcer in 62 cases (26.16%), nonspecific inflammation in 50 cases (21.10%) and diverticulum in 35 cases (14.77%). In the top 5 disease of jejunum, there were 22 cases of jejunitis (22.22%), 15 cases of malignant tumor (15.15%), 14 cases of jejunal ulcer (14.14%), 9 cases of jejunal telangiectasia (9.09%) and 7 cases of jejunal stromal tumor (7.07%). The top five disease of ileum were ileal ulcer in 48 cases (34.78%), ileal diverticulum in 29 cases (21.01%), ileitis in 28 cases (20.29%), ileal telangiectasia in 10 cases (7.25%) and ileal capillary malformation in 5 cases (3.62%). The proportion of males in group B was higher than that in group A (χ2 =14.640, P<0.01). The increasing trend of patients with jejunal and ileal diseases was more obvious in group B. Conclusion In the past 10 years, the incidence of jejunal and ileal diseases shows an increasing trend, and the attention should be paid to the differences between males and females with jejunal and ileal diseases.
keywords: Jejunum Ileum Disease spectrum
文章编号： 中图分类号：R574.5 文献标志码：A
基金项目:国家自然科学基金项目（8176100564）；宁夏回族自治区重点研发计划项目(2018YBZD1554)
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