Abstract:Objective To compare and analyze the clinical effects and influencing factors of different lacrimal catheter treatment for congenital lacrimal duct obstruction after probe insertion failure.? Methods The clinical data of child patients with congenital lacrimal duct obstruction (192 single-eyes)underwent lacrimal passage failure were collected from March 2013 to March 2015. According to the different probing of lacrimal passage surgery, a total of 192 eyes were divided into Ritleng group (Ritleng lacrimal duct catheterization, n=96) and Crawford group (Crawford lacrimal duct catheterization, n=96). Based on the improvement of the patient′s symptoms and the results of fluorescein dye disappearance test (FDDT), the therapeutic effect were compared, and the related factors were analyzed between two groups. Patients with invalid treatment were subdivided into Ritleng failure group and Crawford failure group and received the treatment method of exchange. The therapy effects and related factors were observed and analyzed between two subgroups.? Results There were no statistically differences in recovery rate, total efficiency and incidence of complications between two groups (all P>0.05). The treatment efficacy was statistically related with different age, disease duration, history of dacryocystitis, purulent secretions, degree of lacrimal duct obstruction and past probing times in Ritleng group (P< 0.05, P<0.01) and with different age and history of dacryocystitis in Crawford group(P<0.05, P<0.01). After exchanging operation method, the success rate of reoperation in Ritleng group was significantly higher than that in Crawford group (68.75% vs 11.76%, P<0.05) and were statistically related with different age, history of dacryocystitis, purulent secretions, degree of lacrimal duct obstruction in Ritleng group(P<0.05, P<0.01) and with different age in Crawford group(P<0.05).? Conclusion Both Crawford lacrimal catheterization and Ritleng lacrimal catheterization can achieve a higher success rate in treating patients with congenital lacrimal duct obstruction after probe insertion failure, but Crawford lacrimal catheterization is better in treating patients with purulent secretions, more complex of obstruction andmore previous probingtimes.