###
中国临床研究:2026,39(2):165-172
←前一篇   |   后一篇→
摘要
本文已被:浏览 80次   下载 153
投稿时间:2025-12-18   网络发布日期:2026-03-04
中文摘要: 糖尿病胃肠神经病变(DGN)是常见且严重的糖尿病慢性并发症之一,可导致胃肠动力紊乱、分泌吸收功能障碍,进而引发顽固性营养不良、体重下降及难以控制的血糖波动,形成持续恶性循环。DGN患病率呈显著上升趋势,成为影响患者健康与长期预后的重要临床问题。由于其早期临床症状多不典型,漏诊率极高,导致治疗不足或方向偏差。目前,医学界对DGN的发病机制认识尚不充分,缺乏规范的诊疗流程,管理水平有待提升。本专家建议围绕DGN的常见临床问题,解析病理生理机制,推动早期识别与精准诊断,阐述综合管理策略,从而为提升DGN的防治能力、延缓或逆转病情、改善患者生活质量与长期预后提供实践指导。
中文关键词: 糖尿病  胃肠  神经病变  诊疗  专家建议
Abstract:Diabetic gastrointestinal neuropathy(DGN)is one of the prevalent and severe chronic complications of diabetes mellitus, characterized by gastrointestinal motility disorders and impaired secretory and absorptive functions. These disturbances often result in refractory malnutrition,weight loss,and unstable glycemic control,thereby establishing a persistent vicious cycle. The prevalence of DGN is increasing steadily,positioning it as a significant clinical challenge that adversely affects patient health and long-term outcomes. Due to the nonspecific nature of its early clinical manifestations,DGN is frequently underdiagnosed,leading to delayed or inappropriate interventions. At present,understanding of the underlying pathophysiological mechanisms remains limited,and standardized diagnostic and therapeutic protocols are lacking,contributing to suboptimal clinical management. This expert recommendation addresses key clinical problems of DGN by elucidating its pathophysiology,advocating for early recognition and accurate diagnosis,and outlining comprehensive management strategies. It aims to provide evidence - based guidance to enhance the prevention and treatment of DGN,facilitate disease modification,and ultimately improve patients’quality of life and long-term prognosis.
文章编号:     中图分类号:R587.2    文献标志码:A
基金项目:
附件
引用文本:
江苏省糖尿病达标管理联盟,江苏省基层卫生协会内分泌专业委员会,江苏省预防医学会糖尿病预防与控制专业委员会,江苏省医学会糖尿病学分会基层学组,南京糖尿病并发症研究会老年分会.糖尿病胃肠神经病变诊治专家建议[J].中国临床研究,2026,39(2):165-172.

用微信扫一扫

用微信扫一扫