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投稿时间:2025-04-03 网络发布日期:2025-11-26
投稿时间:2025-04-03 网络发布日期:2025-11-26
中文摘要: 目的 分析主动脉内球囊反搏(IABP)在急性心肌梗死(AMI)合并心源性休克或急性心力衰竭(AHF)应用的合适时机和适用人数。方法 回顾性分析2016年6月至2024年6月于南京江北医院行冠状动脉造影(CAG)和经皮冠状动脉介入术(PCI)患者的临床资料。结果 共有 256 例患者行急诊 PCI,其中置入 IABP 导管的 21例。21例患者中,住院期间死亡7例(死亡组),存活14例(存活组);因心源性休克置入13例(休克组),因AHF置入8例(AHF组)。死亡组患者均为大范围心肌供血的主支血管闭塞,IABP在PCI前置入6例(6/7)。死亡组和存活组在AMI合并症(合并心源性休克或AHF)以及罪犯病变上差异有统计学意义(P<0.05)。休克组中,IABP术前置入11例(11/13);AHF组中PCI术前置入6例(6/8)。休克组与AHF组在梗死部位、低密度脂蛋白胆固醇水平、右室临时起搏占比及IABP使用时间上差异有统计学意义(P<0.05)。结论 在AMI合并心源性休克或AHF行急诊PCI,常规药物不能维持血流动力学时,应在PCI前置入IABP,尤其是存在大范围心肌供血的主支血管闭塞的情况下。
Abstract:Objective To analyze the appropriate timing and patient selection for the use of intra-aortic balloon pump(IABP)in acute myocardial infarction(AMI)complicated with cardiogenic shock or acute heart failure (AHF).Methods A retrospective analysis was conducted on the clinical data of patients who underwent coronary angiography(CAG)and percutaneous coronary intervention(PCI)at Nanjing Jiangbei Hospital from June 2016 to June 2024.Results A total of 256 patients underwent emergency PCI,among which 21 received IABP insertion. Of these 21 patients,7 died during hospitalization(death group),and 14 survived(survival group). IABP was inserted in 13 patients due to cardiogenic shock(shock group)and in 8 patients due to AHF(AHF group). All patients in the death group had extensive myocardial ischemia due to occlusion of the main artery,with IABP inserted before PCI in 6 cases(6/7). There were statistically significant differences between the death group and survival group in terms of AMI complications(complicated by cardiogenic shock or AHF)and culprit lesion(P<0.05). In the shock group,IABP was inserted in 11 patients(11/13)before PCI,while in the AHF group,6 patients(6/8)had IABP inserted before PCI.There were statistically significant differences between the shock and AHF groups in terms of infarct location,low-density lipoprotein cholesterol levels,proportion of right ventricular temporary pacing,and IABP use duration(P<0.05). Conclusion In emergency PCI for AMI complicated with cardiogenic shock and AHF,IABP should be inserted before PCI when routine medication failed to maintain the hemodynamic stability,especially in cases with extensive myocardial ischemia due to occlusion of the main coronary artery.
keywords: Intra⁃aortic balloon pump Acute myocardial infarction Cardiogenic shock Acute heart failure Percutaneous coronary intervention Main artery occlusion
文章编号: 中图分类号:R541.4 文献标志码:A
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引用文本:
张向明,张小兵,刘丹丹,夏思良.主动脉内球囊反搏在急性心肌梗死合并心源性休克或心力衰竭患者中的应用[J].中国临床研究,2025,38(11):1756-1760.
张向明,张小兵,刘丹丹,夏思良.主动脉内球囊反搏在急性心肌梗死合并心源性休克或心力衰竭患者中的应用[J].中国临床研究,2025,38(11):1756-1760.
