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中国临床研究:2025,38(10):1563-1566
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呼和浩特地区三酰甘油-葡萄糖指数与泌尿系结石的相关性分析
(内蒙古自治区人民医院肾内科,内蒙古 呼和浩特 010017)
Correlation analysis between triglyceride-glucose index and urinary stones in Hohhot
(Department of Nephrology,Inner Mongolia Autonomous Region People’s Hospital,Hohhot,Inner Mongolia 010017,China)
摘要
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投稿时间:2024-12-28   网络发布日期:2025-10-20
中文摘要: 目的 分析呼和浩特地区三酰甘油-葡萄糖(TyG)指数与泌尿系结石之间的相关性,为TyG指数的临床运用提供一定数据支持。方法 回顾性收集2021年1月1日至2024年6月1日于内蒙古自治区人民医院住院诊治的151例泌尿系结石患者为研究组,以120名健康体检者作为对照组,分析TyG指数与泌尿系结石之间的相关性。结果 观察组的男性占比、年龄、三酰甘油(TG)、TyG指数、血肌酐(Scr)、TG/高密度脂蛋白胆固醇(HDL-C)高于健康对照组,HDL-C低于健康对照组,差异有统计学意义(P<0.05)。单因素logistic回归分析结果示,TyG指数、TG、TG/HDL-C、HDL-C、空腹血糖(FBG)、年龄、性别、Scr为泌尿系结石发生的影响因素(P<0.05)。进一步多因素logistic回归分析结果显示,TyG指数和Scr高、年龄大、男性是泌尿系结石发生的独立危险因素(P<0.05),而TC高为泌尿系结石发生的独立保护因素(P<0.05)。绘制受试者工作特征曲线,计算曲线下面积,结果显示,TyG指数、Scr、年龄对泌尿系结石具有较好的预测价值,其中TyG指数的最佳截断值为8.905,其敏感性及特异性分别为0.623、0.756。结论 TyG指数与泌尿系结石的发生相关,其为泌尿系结石发生的独立危险因素,并且有一定的预测价值。
Abstract:Objective To analyze the correlation between triglyceride - glucose(TyG)index and urinary stones in Hohhot and provide some data support for the clinical use of TyG index. Methods A total of 151 patients with urinary stones admitted to Inner Mongolia Autonomous Region People 's Hospital from January 1,2021 to June 1,2024 were retrospectively collected,and 120 healthy people were taken as the control group. The correlation between TyG index and urinary stones was analyzed. Results In the observation group,the male proportion,age,triacylglycerol(TG),TyG index,serum creatinine(Scr)and TG high density lipoprotein cholesterol(HDL-C)were higher than those in the control group,and HDL-C was lower than that in the control group,with statistical significance(P < 0.05). Univariate logistic regression analysis showed that TyG index,TG,TG/HDL - C,HDL - C,fasting blood glucose(FBG),age,gender and Scr were the influencing factors of urinary stones(P < 0.05). Further multivariate logistic regression analysis showed that high TyG index and Scr,old age and male were independent risk factors for urinary stones(P <0.05),while high TC was a protective factor for urinary stones(P < 0.05). The receiver operating curve(ROC)curve was drawn and the area under the curve(AUC)value was calculated,and the Results showed that TyG index,Scr and age had good predictive value for urinary stones. The best cut-off value of TyG index was 8.905,and its sensitivity and specificity were 0.623 and 0.756,respectively. Conclusion TyG index is related to the development of urinary stones,which is a risk factor for urinary stones and has certain predictive value.
文章编号:     中图分类号:R691.4    文献标志码:A
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引用文本:
韩云彪,赵晔,朱立革,徐丽斌,于磊,张慧.呼和浩特地区三酰甘油-葡萄糖指数与泌尿系结石的相关性分析[J].中国临床研究,2025,38(10):1563-1566.

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