本文已被:浏览 197次 下载 150次
投稿时间:2024-08-19 网络发布日期:2025-08-20
投稿时间:2024-08-19 网络发布日期:2025-08-20
中文摘要: 目的 探讨影响下腔静脉滤器植入术(IVCFI)后通畅率的因素,并构建预测模型。方法 选取2020年10月至2024年2月阜阳市第二人民医院行IVCFI 术的154例下肢静脉血栓栓塞(VTE)患者作为研究对象,收集患者临床资料,采用单因素和多因素logistic 回归分析IVCFI 术后通畅率<50%的危险因素,并建立列线图模型。结果 糖尿病(OR =5.496,95%CI:1.727~17.489)、药物溶栓(OR =4.749,95%CI:1.998~11.289)、卧床时长≥24 h(OR =3.880,95%CI:1.684~8.937)、纤维蛋白原≥4 g/L(OR =4.401,95%CI:1.558~12.431)和血小板计数≥300×109/L(OR =3.674,95%CI:1.603~8.423)是下肢VTE 患者IVCFI 术后通畅率<50%的独立危险因素(P<0.01)。模型验证结果显示,C-index 为 0.807,校准曲线趋近于理想曲线;受试者工作特征曲线下面积(AUC)为 0.811(95%CI:0.773~0.849);决策曲线示阈值概率为10%~99%范围内,模型预测结果的净获益较高。结论 IVCFI 术后通畅率<50%的危险因素包括糖尿病、药物溶栓、卧床时长≥24 h、纤维蛋白原≥4 g/L和血小板计数≥300×109/L,基于危险因素建立的列线图模型对IVCFI 术后通畅率<50%的发生风险具有良好的预测能力。
Abstract:Objective To explore the factors affecting the patency rate after inferior vena cava filter implantation(IVCFI),and to construct a predictive model. Methods A total of 154 patients who underwent IVCFI in No.2 People's Hospital of Fuyang City from October 2020 to February 2024 were selected as the research objects. The clinical data were collected. The risk factors of patency rate < 50% after IVCFI were analyzed by univariate and multivariate logistic regression,and the nomogram model was established. Results Diabetes(OR=5.496,95%CI:1.727-17.489),drug thrombolysis(OR=4.749,95%CI:1.998-11.289),length of stay in bed ≥ 24 h(OR=3.880,95%CI:1.684-8.937),fibrinogen ≥ 4 g/L(OR =4.401,95%CI:1.558-12.431)and platelet count ≥ 300 × 109/L(OR=3.674,95%CI:1.603-8.423)were independent risk factors for the patency rate < 50% after IVCFI(P<0.01). The model verification results showed that the C - index was 0.807,the calibration curve approached the ideal curve,the area under the receiver operating characteristic curve(AUC)was 0.811(95%CI:0.773-0.849);the decision curve showed that the net benefit of the model??s predictions was higher when the threshold probabilities of 10% to 99%. Conclusion Risk factors for patency rate <50% after IVCFI include diabetes,drug thrombolysis,length of stay in bed ≥ 24 h,fibrinogen ≥ 4 g/L
and platelet count ≥ 300 × 109/L,the nomogram model based on risk factors has good predictive ability for the risk of patency rate < 50% after IVCFI.
keywords: Venous thromboembolism Inferior vena cava filter Postoperative patency rate Risk factors Nomogram
文章编号: 中图分类号:R364.1+5 文献标志码:A
基金项目:
附件
| Author Name | Affiliation |
| GAO Ziyang,ZHU Tao | Interventional Diagnosis and Treatment Center,Anhui Medical University Fuyang Clinical College,No.2 People's Hospital of Fuyang City,Fuyang,Anhui 236000,China |
引用文本:
高子洋,祝涛.下腔静脉滤器植入术后通畅率预测模型的建立[J].中国临床研究,2025,38(8):1242-1245,1250.
高子洋,祝涛.下腔静脉滤器植入术后通畅率预测模型的建立[J].中国临床研究,2025,38(8):1242-1245,1250.
