Abstract:Objective To investigate current status of early enteral nutrition intolerance in patients with post- stroke dysphagia and analyze its influencing factors，and to optimize nutritional support strategies and improve clinical outcomes for post-stroke patients with dysphagia. Methods A total of 260 patients with post-stroke dysphagia in the Affiliated Hospital of Inner Mongolia Medical University were enrolled as the research objects from January 2022 to August 2023. The current status of early enteral nutrition intolerance was investigted. According to presence or absence of feeding intolerance，patients were divided into intolerance group（n=67）and tolerance group（n=193）. The general data of the two groups were compared. The independent risk factors of early enteral nutrition intolerance were analyzed by logistic regression analysis. Results The total incidence of enteral nutrition intolerance in patients with post-stroke dysphagia was 25.77%（67/260）. In all types of intolerance，incidence of diarrhea was the highest（8.46%），followed by abdominal distension（5.77%），reflux and gastric retention（4.23%），vomiting（3.46%）and constipation（2.31%）.The results of logistic regression analysis showed that age ≥60 years（OR=4.141，95% CI=2.021- 8.486），intestinal infection （OR=2.713，95% CI=1.327- 5.548) and mild hypothermia therapy （OR=4.289，95% CI=2.093- 8.788) were independent risk factors of early enteral nutrition intolerance（P＜0.05）. Conclusion The occurrence of early enteral nutrition intolerance is related to advanced age，intestinal infection and mild hypothermia therapy in patients with post-stroke dysphagia.