Abstract:Objective This paper uses data mining to study the correlation between acupoint selection law of meridians and signs of Yang deficiency in clinical medical records of contemporary famous acupuncturists, and to explore the association rules between Yang deficiency and diseases and meridians. Methods The literature on the application of acupuncture and moxibustion in the treatment of diseases related to Yang deficiency syndrome from January 1, 1990 to January 1, 2020 in CNKI were searched. Aprior algorithm was used to study the association rules. Results A total of 82 research literatures and 72 medical records were included, involving 91 cases and 163 diagnoses, 28 syndrome types, 406 clinical symptoms, 141 acupoints and 14 meridians. The common signs of Yang deficiency syndrome were fat body, sour waist, poor appetite, mental fatigue, chilly limbs, clear and long urination, poor sleep, etc. The commonly used acupoints belonged to conception vessel, the leg sunlight Yang stomach meridian, the governor vessel, leg greater Yang bladder maridian, etc. Conclusion This study is conducive to making the fuzziness of Chinese medicine syndrome and signs more data-based and objective. It is more conducive to open up ideas for the research of objective identification and treatment of disease and syndrome.